Basics of Salivary Gland Tumors - A Review
Authors:
Dr.Nikita Ravindra Kamble,
Dr. Sandhya Tamgadge,
Format: Paperback | Genre : Medical Science | Other Book Detail
Format: Paperback | Genre : Medical Science | Other Book Detail
Salivary glands are essential organs that discharge a fluid secretion and
especially saliva into the mouth cavity and that in humans comprise large
compound racemose glands including the parotid glands, the sublingual
[1] glands, and the submandibular glands. During gland morphogenesis, many
developmental processes involve a series of coordinated movements and
reciprocal interactions between the epithelium and mesenchyme that
generate the ductal system and the secretory units. Salivary gland tumours
begin when some cells in a salivary gland develop changes (mutations) in their
DNA. A cell's DNA contains the instructions that tell a cell what to do. The
changes tell the cells to grow and divide rapidly. The abnormal cells go on living
when healthy cells would die. The accumulating cells form a tumour. If
additional changes happen in the DNA, the abnormal cells may become
cancerous. Cancer cells can invade and destroy nearby tissue. They can also
break away from the tumor and spread (metastasize) to distant areas of the
[2] body. Salivary gland tumours are rare and the majority of these neoplasms are
benign and only 20% are malignant. The annual incidence of salivary gland
[3]. cancers ranges from 0.5 to 2 per 100,000 in different parts of the world The sex
distribution for salivary gland cancers is equal, and the majority of the cases arise
[3] in the sixth decade. Tumours can occur in both the major and minor salivary
glands. 80% of major salivary gland tumours occur in the parotid glands, while
most minor [3]
Book Also Available On
Share: