Login

Osteoarthritis (OA) is primarily a cartilage disease as it is characterized by the progressive loss of hyaline articular cartilage. Ultimately, the articular cartilage degenerates with fibrillation, fissures, ulceration, and full thickness loss of the joint surface.1 Common sites developing OA include the knee, hand, hip, spine and foot. Among these, the knee is the most commonly affected joint, and knee OA patient present with a combination of inflammation, pain, stiff ness, muscle atrophy and deformity.2